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InChiKey: ZNOVTXRBGFNYRX-STQMWFEESA-N
214(2):258-64
GDC-0349 was orally dosed to mice at 30-80 mg/kg once per day
InChi: InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H
InChi: InChI=1S/C14H17N3O4/c15-7-12(18)17-8-10(6-11(17)14(20)21)16-13(19)9-4-2-1-3-5-9/h1-5
D609 - CAS# 83373-60-8 tin-3'-sulfonate InChiKey: ZNOVTXRBGFNYRX-STQMWFEESA-ND 609, also known as D 609 free, is a phospholipase C inhibitor potentially for the treatment of pancreatic cancer. D 609, an inhibitor of PC PLC and sphingomyelin synthase, strongly inhibited myogenic tone and had no effect on depolarization induced contraction. D 609 appeared to act by lowering cytoplasmic Ca(2+) concentration to levels below those that activate contraction. Product information CAS Number: 83373 60 8 Molecular Weight: 266. 46
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