Indirubin-3'-monoxime - CAS# 160807-49-8 10745 A phase I and pharmacodynamic

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Formula: C17H17ClFN3O3

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Indirubin-3'-monoxime - CAS# 160807-49-8 10745 A phase I and pharmacodynamicIndirubin 3' monoxime is a potent GSK 3 inhibitor, and weakly inhibits 5 Lipoxygenase, with IC50s of 22 nM and 7. 8 10 M, respectively; Indirubin 3' monoxime also shows inhibitory activities against CDK5 p25 and CDK1 cyclin B, with IC50s of 100 and 180 nM. Product information CAS Number: 160807 49 8 Molecular Weight: 277. 28 Formula: C16H11N3O2 Synonym: Indirubin 3' oxime Chemical Name: (E, 3E) 3 (hydroxyimino) 1', 2' dihydro 1H, 3H [2, 3'