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LY-303511 is a negative control compound with respect to PI3K activity
24-12)16(18)22/h8
van de Wouwer M
2019 Apr 1
Smiles: OC1CCC(CC1)NC1=NC2=C(C=N1)N=C(NC1C(F)=CC(F)=CC=1F)N2[C@@H]1COCC1
SR-59230A oxalate - CAS# 174689-39-5 Catalog No.:M7124-2 LY-303511 is a negative controlSR 59230A oxalate, CAS No. 174689 39 5, is a potent and selective 3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for 3, 1 and 2 receptors respectively). SR 59230A was subsequently shown to also act at 1 adrenoceptors at high doses. It has been shown to block the hyperthermia produced by MDMA in animal studies. SR 59230A blocks MDMA induced hyperthermia, while at high concentrations it blocks hyperthermia but also increases heat loss