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7 μM (n=4)
27(9):1685-95
has potent expectorant effects
it may inhibit the activity of multiple kinases
Target: mAChR
Foropafant DO-TFEA 7 μM (n=4)Foropafant (SR27417) highly potent, competitive, selective and orally active antagonist of platelet activating factor (PAF) receptor, with a Ki value of 57 pM for [3H]PAF binding, at least 5 fold lower than that of unlabeled PAF itself. Foropafant potently inhibits PAF induced aggregation of rabbit and human platelets. Product information CAS Number: 136468 36 5 Molecular Weight: 464. 71 Formula: C28H40N4S Chemical Name: N [2 (dimethylamino)ethyl] N
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