![Gliotoxin Size:10mg solid Chemical Name: 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M11737_1624941568.gif?v=1624941569)
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Chemical Name: 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1
Larochelle S
also known as Ramosetron and YM-060
Pulm Pharmacol Ther
InChi: InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6
Gliotoxin Size:10mg solid Chemical Name: 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A. fumigatus, inhibits the phagocytosis of macrophages and the immune functions of other immune cells. Gliotoxin inhibits inducible NF B activity by preventing IB degradation, which consequently induces host cell apoptosis. Gliotoxin activates PKA and increases intracellular cAMP concentration; modulates actin cytoskeleton rearrangement to facilitate A. fumigatus